PHARMACOLOGY ATI TEST

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Digoxin INSERT INTO `cofwp_posts` VALUES (lanoxin)Antidysrhythmic
Side Effect: Blurred or doubled vision
GuaifenesinSide Effect: Can cause drowsiness
Estrogen INSERT INTO `cofwp_posts` VALUES (premarin)Side Effect: Increase Risk of Thromboembolism with shortness of breath, severe headache, vomiting.
Sudden acute pain in the calves, legs, chest, abdomen

Doxepin INSERT INTO `cofwp_posts` VALUES (Sinequan)Anticholinergic
Side Effect: Urinary retention, constipation, drying of nasal/oral secretions, Increased Heart Rate
Albuterol INSERT INTO `cofwp_posts` VALUES (Proventil)Sympathomimetic; Adrenergic beta-2 agonist
Contraindicated; with MAOI – can increase action of albuterol leading to hypertension crisis.
Beta blockers – can inhibit the therapeutic effects
USE: invert canister, shake before use, rinse mouth after use, with new inhaler perform test spray.
Levothyroxine INSERT INTO `cofwp_posts` VALUES (T4) essay writer in ukIndication: HYPOthyroidism in relation to dysfunction of hypothalamus, pituitary or thyroid gland
Cephalosporins INSERT INTO `cofwp_posts` VALUES (Keflex)Allergy to cephalosporins is considered a precaution for taking penicillins
Phenobarbital INSERT INTO `cofwp_posts` VALUES (Barbiturates)Interventions for anticonvulsant therapy; assess for respiration, depression, excess sedation from toxic effects, Intravenous INSERT INTO `cofwp_posts` VALUES (IV) at less than 50 mg per minute, avoid extravasation INSERT INTO `cofwp_posts` VALUES (alkaline can cause skin damage)
Sumatriptan INSERT INTO `cofwp_posts` VALUES (Imitrex)USE: When migraine symptoms appear and again in 1 hour if symptoms persist
Fastest Route for Pharmacological AdministrationINTRAVENOUS
NARCANINSERT INTO `cofwp_posts` VALUES (OPIOID ANTAGONIST)
Therapeutic action: improvement of respiratory rate
Baclofen INSERT INTO `cofwp_posts` VALUES (Lioresal)Therapeutic action: Decreases frequency and severity of muscle spasms
Erythromycin INSERT INTO `cofwp_posts` VALUES (Erythrocin)Macrolide
Side Effect: Liver Toxicity
Insulin: INSERT INTO `cofwp_posts` VALUES (high dose) U-5005 times stronger than u-100 – divide dosage ordered by 5
Spirinolactone INSERT INTO `cofwp_posts` VALUES (Aldactone)Potassium sparing diuretic
Avoid foods with high potassium such as salt substitutes
Chloroquine phosphate INSERT INTO `cofwp_posts` VALUES (Aralen)Indication: Malaria prevention
Use: Take weekly starting 1 week before departure and continued for 4 weeks after return
Heparin INSERT INTO `cofwp_posts` VALUES (anticoagulant)Use with ALTEPLASE for acute Myocardial Infarction
Warfarin INSERT INTO `cofwp_posts` VALUES (Coumadin)Use: Long term prophylaxis of thrombosis
Antidote: Vitamin K
Clopidogrel INSERT INTO `cofwp_posts` VALUES (Plavix)Use: Reduce long-term risk of clotting w/atherosclerosis and recent MI of CVA
Alteplase INSERT INTO `cofwp_posts` VALUES (Activase)Antithrombolytic
Use: Acute MI/ CVA INSERT INTO `cofwp_posts` VALUES (has short half-life)
Methylphenidate INSERT INTO `cofwp_posts` VALUES (Concerta)USE: Narcolepsy
Precaution: Avoid caffeine
Testosterone IMIf used to correct delayed puberty, assess bone maturation with bi-annual x-rays of hand and wrist; monitor liver function; can increase hypoglycemia, potentiate sleep apnea, exacerbate heart failure due to fluid retention
Diphenoxylate and Atropine INSERT INTO `cofwp_posts` VALUES (Lomotil)Caution: With Renal impairment, decreased elimination of Atropine thereby increasing anticholinergic effects of atropine like confusion
Loperamide INSERT INTO `cofwp_posts` VALUES (Imodium)Use: Anti-diarrheal INSERT INTO `cofwp_posts` VALUES (poorly absorbed from GI tract; difficulty crossing the blood-brain barrier)
Methylcellulose INSERT INTO `cofwp_posts` VALUES (Citrucel)Bulk-forming agent with minimal Side Effects
Psyllium INSERT INTO `cofwp_posts` VALUES (Metamucil)Bulk-forming agent with minimal Side Effects
Acetazolamide INSERT INTO `cofwp_posts` VALUES (Diamox) – diureticIndication – edema, epilepsy, acute mountain sickness, glaucoma INSERT INTO `cofwp_posts` VALUES (decrease intraocular pressure due to decreased amounts of aqueous humor in the eye)
Contraindication: allergy to sulfonamides
Metoprolol INSERT INTO `cofwp_posts` VALUES (Lopressor) – Beta BlockerHold dose for dyspnea INSERT INTO `cofwp_posts` VALUES (sign of exacerbation of Cardiac Heart Failure)
Propanolol INSERT INTO `cofwp_posts` VALUES (Inderal) – Beta BlockerUSE: Dysrhythmia, hypertension, angies
Side Effects: bronchoconstriction, bronchospasm, can block glycogenesis
Norgestrel INSERT INTO `cofwp_posts` VALUES (Ovrette)USE: Contraception
Side Effects: Excess progestin, weight gain from increased appetite; deficiency of progestin; late breakthrough bleeding, amenorrhea, excess estrogen that leads to edema
Medroxyprogesterone INSERT INTO `cofwp_posts` VALUES (Provera) – female hormoneContraindication: smoking/tobacco products
RISKS: Thromboembolism and Cardiovascular complications
Interventions: use additional contraceptive measures with antibiotic therapy
IM Injection Sitelocate dorsogluteal site
Nausea – therapyAntiemetic plus cool damp cloth to forehead, neck and wrists
Allopurinol INSERT INTO `cofwp_posts` VALUES (Zyloprim)Indication: Gout
Mechanism of Action: decreases serum uric acid levels and urinary uric acid secretion
Precaution: avoid foods that acidify urine such as CORN
Tuberculosis INSERT INTO `cofwp_posts` VALUES (TB) multi-drug TherapyIsoniazid INSERT INTO `cofwp_posts` VALUES (INH)
Rifampin, pyrazinamide, ethambutol – to deal with resistant strains
Lisinopril INSERT INTO `cofwp_posts` VALUES (Zestril) ACE InhibitorsSide Effects: dry/persistent cough for 1 to 2 weeks from increased bradykinin
Synergistic drugsEffects of giving both drugs are more than the effect of individual drugs taken separately
Furosemide INSERT INTO `cofwp_posts` VALUES (Lasix) – loop diureticsIntervention: Check Blood Pressure before giving to determine baseline.
Can cause decreased blood pressure due to decreased circulatory volume by relaxing venous smooth muscle.
Ticlopidine INSERT INTO `cofwp_posts` VALUES (Ticlid)Indication: Prevent coronary artery thrombosis
Intervention: Check platelet count
PRBC INSERT INTO `cofwp_posts` VALUES (packed red blood cells)Used as blood replacement when fluid overload is a concern
IV INSERT INTO `cofwp_posts` VALUES (intravenous) medicationsIntervention: Assess site for redness and swelling before adminisration
Collagenase INSERT INTO `cofwp_posts` VALUES (Santyl)USE: Debride Ulcers
InterferonUSE: Prevent viral replication
Isotretinoin INSERT INTO `cofwp_posts` VALUES (Accutane)Contraindication: Pregnancy with two forms of birth control due to teratogenic effects
VaccineAdvice of live versus attenuated or killed vaccine: long lasting active immunity versus partial INSERT INTO `cofwp_posts` VALUES (passive)
Epoetin Alfa INSERT INTO `cofwp_posts` VALUES (Procrit)Indication: Treat anemia
Side Effects: Headache, Hypertension, seizures in relation to INSERT INTO `cofwp_posts` VALUES (Hct) hematocrit rises too quickly
Urofollitropin INSERT INTO `cofwp_posts` VALUES (Fertinex)Dosage: administration IM based based in preceding cycles
Side Effect: ovarian hyperstimulation syndrome
Hypertensive crisisSigns and Symptoms: Flushed skin, headache, visual changes
Acetylcysteine INSERT INTO `cofwp_posts` VALUES (Mucomyst)Indication: Prevent liver damage following acetaminophen INSERT INTO `cofwp_posts` VALUES (Tylenol) overdose. Most effective if given shortly after ingestion; some protection up to 24 hours.
Montelukast INSERT INTO `cofwp_posts` VALUES (Singulair)Indication: prevent asthma exacerbations
Dose: Daily at bedtime
Side Effects: Well tolerated
Metoclopramide INSERT INTO `cofwp_posts` VALUES (Reglan)Has increased sedation when given with Morphine
Mannitol INSERT INTO `cofwp_posts` VALUES (Osmitrol) – diureticsCaution with patients with heart disease. Can precipitate CHF and pulmonary edema
Opiate OverdoseCauses Respiratory Depression.
Narcan Antidote shorter acting. May need less than 1 dose
Diphenhydramine INSERT INTO `cofwp_posts` VALUES (Benadryl)Precaution: Avoid other CNS depressants such as alcohol, benzodiazepines, kava kava
AnaphylaxisSigns and Symptoms: bronchoconstriction, angioedema, hypotension
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